Progesterone Receptor Gene (PROGINS) Polymorphism Correlates with Late Onset of Migraine
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چکیده
منابع مشابه
Association of Alu Insertion Polymorphism in Progesterone Receptor Gene with Risk of Multiple Sclerosis
Background and purpose: Multiple sclerosis (MS) is a chronic autoimmune disease in which the myelin sheaths of nerve cells in the brain and spinal cord are damaged. The prevalence of disease is higher in women and it seems that sex hormones, which usually exert their effects through receptors, are involved in susceptibility to MS. Considering the functional role of Alu insertion 306 bp polymorp...
متن کاملFrequency of Polymorphism Alu Insertion in Progesterone Receptor Gene in Endometriosis
Background and Aims: This research aimed to study a possible link between endometriosis and polymorphism of the progesterone receptor gene. Materials and Methods: The control group consisted of 86 women without endometriosis and the case group comprised 86 patients with a diagnosis of endometriosis by laparoscopy. Genotypes for Alu insertion polymorphisms (A1/A1, A1/A2 and A2/A2) were descri...
متن کاملThe progins progesterone receptor gene polymorphism is not related to endometriosis‐associated infertility or to idiopathic infertility
OBJECTIVE This study aimed to determine the frequency of the PROGINS polymorphism in women with endometriosis-associated infertility, in infertile women without endometriosis and in controls. INTRODUCTION The human progesterone receptor gene has two isoforms that modulate the biological action of progesterone: isoform A, which is capable of inhibiting the activation of the estrogen receptors,...
متن کاملassociation of calhm1 gene polymorphism with late onset alzheimer’s disease in iranian population
alzheimer's disease (ad) is a genetically heterogeneous neurodegenerative disease and late-onset type (load) is the most common form of dementia affecting people over 65 years old. calhm1 (p86l) encodes a transmembrane glycoprotein that controls cytosolic ca2+ concentrations and aß levels and p86l polymorphism in this gene is significantly associated with load in independent case controls in a ...
متن کاملThe progesterone receptor PROGINS polymorphism is not related to oxidative stress factors in women with polycystic ovary syndrome
BACKGROUND Women with PCOS have been reported to be at increased risk of a number of gynaecological neoplasias, including endometrial, breast, and ovarian cancer. Studies of the possible association of genetic variation in progesterone receptor polymorphism with risk of ovarian and breast cancer have concentrated on a variant known as PROGINS. METHODS Ninety-five young women with PCOS and 99 ...
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ژورنال
عنوان ژورنال: DNA and Cell Biology
سال: 2015
ISSN: 1044-5498,1557-7430
DOI: 10.1089/dna.2014.2534